Key result
Catheter ablation for PVCs achieves ~88% sustained success with low major complication rates.
Why the study?
Premature ventricular complexes are common arrhythmias and catheter ablation is a major treatment, motivating this evaluation of clinical experience and procedural outcomes.
Does radiofrequency catheter ablation reduce PVC burden in patients with symptomatic premature ventricular complexes?
Observational (n=645)
No
Does radiofrequency catheter ablation reduce PVC burden in patients with symptomatic premature ventricular complexes?
Catheter ablation is a highly successful and safe treatment modality for symptomatic premature ventricular complexes, particularly those originating from the right or left ventricular outflow tracts.
Supports ablation feasibility for symptomatic PVCs; leaves open confirmation of burden reduction in randomized trials.
Objective: Premature ventricular complexes (PVCs) are common arrhythmias and catheter ablation (CA) is the major treatment in patients with PVCs. In this study, we aimed to share our experience on PVCs patients who had undergone CA. Patients and Methods: We investigated consecutive patients who had undergone CA because of PVCs between January 2015 and March 2021 in a single centre arrhythmia unit. Patients’ characteristics, rhythm Holter recordings, echocardiography results and CA outcomes were noted. Patients were followed up for 22.3±3.7 months. Descriptive statistics were used to demonstrate features of study patients. Results: Study population consisted of 645 patients; mean age was 51 ± 4.14 and 372 (57.7%) were male. Arrhythmia originated from the right ventricular outflow tract in 279 (46.6 %) patients, coronary cusps in 161 (26.9 %) patients, left ventricle summit in 50 (8.3%) patients and inside of the right or left ventricle in remaining patients. Sustained procedural success was achieved in 526 (88.1 %) patients. Recurrence was observed in 46 (6.7%) patients during follow-up. Major complication occurred in two patients (one procedural mortality due to coronary artery injury and one tamponade). Conclusion: Premature ventricular contraction ablation can be utilized safely with high success rate. Most PVCs originate from the right or left ventricular outflow tract.
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Demır et al. (2023) conducted an observational in Premature ventricular complexes (PVCs) (n=645). Catheter ablation was evaluated on Sustained procedural success (persistent elimination of ≥80% of PVC burden or absence of VT). Catheter ablation for premature ventricular complexes achieved a sustained procedural success rate of 88.1% after all ablation attempts, with a low major complication rate.
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