Key result
TDI-derived isovolumic myocardial acceleration ≤2.7 m/sec² distinguished COPD patients from controls with 81% sensitivity and 98% specificity.
Why the study?
Does tissue Doppler imaging-derived isovolumic myocardial acceleration accurately detect early right ventricular systolic dysfunction in patients with COPD?
Population
130 subjects including 90 patients with chronic obstructive pulmonary disease and 40 controls
Comparison
Tissue Doppler imaging-derived right ventricular… vs Controls without COPD
Design
Cross-sectional
Authors
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IVA may detect subclinical RV dysfunction in COPD; leaves open prospective validation before clinical use.
Cross-Sectional (n=130)
Does tissue Doppler imaging-derived isovolumic myocardial acceleration accurately detect early right ventricular systolic dysfunction in patients with COPD?
p-value: p=0.0001
TDI-derived RV isovolumic myocardial acceleration (IVA) is a useful noninvasive echocardiographic parameter for detecting subclinical right ventricular dysfunction in patients with COPD.
Tayyareci et al. (2009) conducted a cross-sectional in Chronic obstructive pulmonary disease (COPD) (n=130). Tissue Doppler imaging (TDI)-derived isovolumic myocardial acceleration (IVA) vs. Controls and COPD patients without right heart failure was evaluated on Distinction between pure COPD and COPD with right heart failure using IVA (p=0.0001). TDI-derived isovolumic myocardial acceleration ≤2.7 m/sec² distinguished COPD patients from controls with 81% sensitivity and 98% specificity.
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