Key result
Total sleep deprivation elicited stable, trait-like individual differences in ocular, ECG, and EEG signals across repeated exposures (ICC range 0.67-0.91).
Why the study?
Are individual differences in physiologic measures stable across repeated exposures to total sleep deprivation in healthy volunteers?
Population
12 healthy ethnic-Chinese male volunteers aged 22-30 years
Design
Cohort
Follow-up
Two separate occasions of at least 26 hours
Authors
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Trait-like responses to sleep deprivation support risk stratification research; leaves open clinical translation or intervention guidance.
Observational (n=12)
Are individual differences in physiologic measures stable across repeated exposures to total sleep deprivation in healthy volunteers?
Effect estimate: ICC 0.67-0.91
Physiologic responses to sleep loss, including heart rate variability and EEG changes, are highly reproducible and trait-like across repeated exposures to sleep deprivation.
Chua et al. (2014) conducted an observational in Healthy (n=12). Total sleep deprivation was evaluated on Stability of individual differences in physiologic measures (PERCLOS, blink rate, heart rate and its variability, and EEG spectral power) (ICC 0.67-0.91). Total sleep deprivation elicited stable, trait-like individual differences in ocular, ECG, and EEG signals across repeated exposures (ICC range 0.67-0.91).
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