Key result
High-power short-duration radiofrequency ablation combined with half-normal saline irrigation resulted in 89% of patients remaining free from atrial arrhythmias over a median 321 days.
Why the study?
Data regarding the use of high-power short-duration RF ablation combined with half-normal saline catheter irrigation are limited.
Does high-power short-duration radiofrequency ablation with half-normal saline irrigation prevent atrial arrhythmias in patients with atrial fibrillation?
Cohort (n=100)
Does high-power short-duration radiofrequency ablation with half-normal saline irrigation prevent atrial arrhythmias in patients with atrial fibrillation?
High-power short-duration radiofrequency ablation combined with half-normal saline irrigation appears safe and effective for atrial fibrillation, achieving an 89% arrhythmia-free survival at approximately 11 months.
Hypothesis-generating for HPSD ablation with half-normal saline in AF; prospective randomized trials needed before clinical adoption.
BACKGROUND: Data regarding the use of high-power short-duration (HPSD) radiofrequency (RF) in combination with half-normal saline irrigation for catheter irrigation are limited. OBJECTIVES: This study investigated the safety and efficacy of using HPSD RF ablation in combination with half-normal saline irrigation for the treatment of AF. METHODS: One hundred consecutive patients with AF underwent RF ablation using HPSD combined with half-normal saline for catheter irrigation. In addition, the following ablation strategies were used: 1 mm tags for the display of ablation lesions on the mapping system, high-frequency jet ventilation (HFJV), low contact force, pacing after ablation to verify areas of noncapture, atrial/ventricular pacing at 500 to 700 ms to aid in catheter stability, use of two skin electrodes to reduce impedance, and postablation adenosine infusion. Power was started at 40 to 45 W and was modulated manually based on impedance changes. The average power and lesion duration were 38.1 ± 3.3 W and 8.1 ± 2.3 s, respectively. During a median follow-up period of 321 ± 139 days, 89% of the patients remained free from any atrial arrhythmias after a single RF ablation procedure. No procedure-related death, stroke, pericardial effusion, or atrioesophageal fistula occurred during follow-up. CONCLUSIONS: Catheter ablation using HPSD RF lesions in combination with half-normal saline irrigation and is safe and effective, and results in high rate of freedom from AF.
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Maan et al. (2021) conducted a cohort in Atrial fibrillation (n=100). High-power short-duration radiofrequency ablation with half-normal saline irrigation was evaluated on Freedom from any atrial arrhythmias. High-power short-duration radiofrequency ablation combined with half-normal saline irrigation resulted in 89% of patients remaining free from atrial arrhythmias over a median 321 days.
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