Propranolol during the evolution and subsequent ten days of myocardial infarction in man: Hemodynamic, initial cardiac energetic, and neurohumoral responses

55 patients with transmural myocardial infarction who did not show significant left ventricular failure

Propranolol 0.1 mg/kg administered intravenously within an average of 8.8 h of transmural myocardial infarction, continued orally with an average dose of 567±20 (SD) mg q6h for 10 days

Hemodynamic, initial cardiac energetic, and neurohumoral responses (including cardiac index, left ventricular ejection fraction, blood pressure, pulmonary capillary wedge pressure, coronary blood flow, myocardial oxygen consumption, and metabolic markers)surrogate