Why the study?
To investigate the two-center feasibility of highly k-t-accelerated 2-minute aortic 4D flow MRI and evaluate its performance for quantifying velocities and wall shear stress.
Does highly accelerated 4D flow MRI (k-t acceleration factor 5) provide feasible and accurate quantification of aortic velocities and wall shear stress compared to conventional 4D flow MRI in healthy volunteers and patients with aortic/cardiac disease?
Does highly accelerated 4D flow MRI (k-t acceleration factor 5) provide feasible and accurate quantification of aortic velocities and wall shear stress compared to conventional 4D flow MRI in healthy volunteers and patients with aortic/cardiac disease?
Highly accelerated 2-minute aortic 4D flow MRI is feasible and significantly reduces scan times, though it may underestimate proximal aortic wall shear stress in patients.
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May enable shorter aortic 4D flow scans clinically; leaves open WSS accuracy for prospective validation.
Bollache et al. (2019) studied this question.
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