Key result
The k-t GRAPPA accelerated 4D-flow sequence significantly reduced mean scan time by 46% compared to standard GRAPPA (9:40 min vs 17:56 min, p=0.002) while providing fewer motion artefacts and comparable flow quantification.
Why the study?
The study aimed to compare two broadly used accelerated 4D-flow sequences with a 2D-flow reference standard in healthy volunteers regarding absolute flow parameters, image quality, and eddy current correction.
Does a k-t GRAPPA accelerated 4D-flow MRI sequence improve scan time and image quality compared to standard GRAPPA without compromising aortic flow quantification accuracy?
Cross-Sectional (n=40)
Blinded reading
Randomized order of reading
No
Does a k-t GRAPPA accelerated 4D-flow MRI sequence improve scan time and image quality compared to standard GRAPPA without compromising aortic flow quantification accuracy?
Effect estimate: 46.12% reduction
Absolute Event Rate: 9.67% vs 17.93%
p-value: p=0.002
k-t GRAPPA accelerated 4D-flow MRI significantly reduces scan time and motion artifacts compared to standard GRAPPA while maintaining high accuracy for aortic flow quantification.
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May improve 4D-flow MRI feasibility in busy clinics; leaves open multicenter validation of diagnostic impact.
Ebel et al. (2019) conducted a cross-sectional in Healthy volunteers (n=40). k-t GRAPPA accelerated 4D-flow sequence vs. Standard GRAPPA 4D-flow sequence was evaluated on Mean acquisition time (46.12% reduction, p=0.002). The k-t GRAPPA accelerated 4D-flow sequence significantly reduced mean scan time by 46% compared to standard GRAPPA (9:40 min vs 17:56 min, p=0.002) while providing fewer motion artefacts and comparable flow quantification.
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