Population
Human plasma samples and recombinant prorenin expressed by L-929 fibroblasts transfected with human renin gene
Design
Preclinical
Authors
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Does not support clinical renin assay changes; leaves open further validation in human hypertension studies.
The monoclonal antibody R1-20-5 is selective for human active renin and enables direct radioimmunoassay measurement that correlates highly with enzymatic activity.
Zuo et al. (1992) studied this question.
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