Why the study?
Does a newly developed IRMA with Remikiren accurately measure plasma renin and prorenin compared to a classical enzyme kinetic assay?
Population
Healthy subjects, patients with primary hyperaldosteronism, renovascular hypertension, low-, medium-, and…
Comparison
Immunoradiometric assays using two monoclonal… vs Classical enzyme kinetic assay
Design
Other
Authors
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May offer a practical alternative for renin/prorenin measurement; leaves open broader validation before clinical adoption.
Does a newly developed IRMA with Remikiren accurately measure plasma renin and prorenin compared to a classical enzyme kinetic assay?
A newly developed IRMA using Remikiren provides a valid and reliable method for measuring plasma renin and prorenin across various clinical conditions.
Derkx et al. (1996) studied this question.
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