September 1, 1982Arteriosclerosis An Official Journal of the American Heart Association IncOpen Access

Roles of lipoprotein lipase and hepatic triglyceride lipase in the catabolism in vivo of triglyceride-rich lipoproteins.

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Structured PICO

Population

22 patients

Intervention

Heparin injection (60 U/kg)

Outcome

Relationship between the activities of hepatic triglyceride lipase and lipoprotein lipase in postheparin plasma and the fractional removal rates of very low density lipoproteins (VLDL) and VLDL remnant particlessurrogate

Lipoprotein lipase, but not hepatic triglyceride lipase, plays a key regulatory role in the catabolism of triglyceride-rich lipoproteins in vivo.

Discussion

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Implication

Supports LPL's regulatory role in triglyceride-rich lipoprotein clearance; cross-sectional data leave causal and therapeutic implications open.

Cite This Study

Reardon et al. (1982) studied this question.

synapsesocial.com/papers/6a1febce91899344c12e56c8 https://doi.org/10.1161/01.atv.2.5.396

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Implication

Supports LPL's regulatory role in triglyceride-rich lipoprotein clearance; cross-sectional data leave causal and therapeutic implications open.

Roles of lipoprotein lipase and hepatic triglyceride lipase in the catabolism in vivo of triglyceride-rich lipoproteins.

Structured PICO

Discussion

Implication

Cite This Study

Roles of lipoprotein lipase and hepatic triglyceride lipase in the catabolism in vivo of triglyceride-rich lipoproteins.

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Also Consider