Why the study?
Does habitual cigarette smoking affect in-hospital mortality in patients with acute myocardial infarction?
Population
7,433 consecutive patients presenting with acute myocardial infarction from 76 hospitals countrywide
Comparison
Habitual cigarette smoking vs Non-smoking
Design
Cohort
Follow-up
In-hospital
Authors
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Age confounds the smoker's paradox in AMI; reinforces cessation emphasis while leaving causal effects open in observational data.
Does habitual cigarette smoking affect in-hospital mortality in patients with acute myocardial infarction?
The apparent survival advantage of smokers after acute myocardial infarction ('smoker's paradox') is largely explained by baseline differences such as younger age, rather than a true protective effect of smoking.
George Andrikopoulos (2001) studied this question.
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