Key result
The saline calibration method for trans-cardiac conductance accurately determined parallel conductance offset volume with a nonsignificant bias of -2.5 ml compared to the zero-volume method.
Population
Anesthetized sheep
Comparison
Trans-cardiac conductance method with saline… vs Conventional intra-cardiac conductance catheter…
Design
Preclinical
Authors
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Saline calibration validates in animals; leaves open clinical translation for LV volume measurement.
Mean Difference: -2.5
Absolute Event Rate: 104% vs 106%
p-value: p=nonsignificant
The saline calibration method accurately determines parallel conductance offset volume for the trans-cardiac conductance method in measuring left ventricular volume, though substantial interanimal variability requires individual calibration.
Staal et al. (2003) studied Anesthetized sheep. Saline calibration method for trans-cardiac conductance vs. Intra-cardiac conductance catheter method (zero-volume method) was evaluated on Parallel conductance offset volume (Vp) (bias -2.5 ml, p=nonsignificant). The saline calibration method for trans-cardiac conductance accurately determined parallel conductance offset volume with a nonsignificant bias of -2.5 ml compared to the zero-volume method.
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