Why the study?
Does a new method based on hypertonic saline dilution curve analysis improve the reproducibility of parallel conductance estimation compared to the conventional method in patients undergoing left ventricular volume measurements?
Does a new method based on hypertonic saline dilution curve analysis improve the reproducibility of parallel conductance estimation compared to the conventional method in patients undergoing left ventricular volume measurements?
A new method for estimating parallel conductance using hypertonic saline dilution curves significantly improves measurement reproducibility, potentially reducing the number of required injections during conductance catheter procedures.
May reduce saline injections in conductance catheter procedures; leaves open effects on LV volume accuracy and outcomes.
OBJECTIVES: To determine absolute ventricular volume with the conductance catheter technique, the electrical conductance of tissues and fluids (parallel conductance) around the ventricle should be determined precisely. METHODS: A new objective method to estimate parallel conductance based on analysis of the dilution curve of hypertonic saline was investigated. The parallel conductances obtained with the new method (G(a)(p)) were compared to those obtained with the conventional method (G(l)(p)). The study was performed in the left ventricle of 12 patients. RESULTS: G(a)(p) was not significantly different from G(l)(p). For the G(l)(p) method the average percentage difference between duplicate values, both taken as absolute values, was 15.06% and for the G(a)(p) method it was 4. 01%. Thus the reproducibility of the method is a factor four better than that of the method. This difference appeared to be significant. CONCLUSION: We conclude that a smaller number of injections will be required to obtain the same precision using our method.
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Lilian Kornet (2000) studied this question.
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