Key result
A young Chinese woman presented with gastric adenocarcinoma revealed by atypical radiographic lesions consistent with both pulmonary lymphangitic carcinomatosis and pulmonary tumour thrombotic microangiopathy.
Case Report (n=1)
Highlights an unusual presentation of gastric adenocarcinoma with atypical radiographic lesions consistent with both pulmonary lymphangitic carcinomatosis and pulmonary tumour thrombotic microangiopathy.
Clinicians should consider gastric malignancy with atypical pulmonary lesions; extends documented spectrum of dual metastatic patterns in young patients.
Pulmonary lymphangitic carcinomatosis (PLC) is a well-known form of tumour metastasis to the pulmonary lymphatic system or to the adjacent interstitial tissue resulting in thickening of the bronchovascular bundle and septa. Another type of tumour metastasis to the lung involves the pulmonary vascular system and is known as pulmonary tumour thrombotic microangiopathy (PTTM). In this article, we will describe the unusual case of a young Chinese woman with gastric adenocarcinoma revealed by atypical radiographic lesions consistent with both PLC and PTTM. We will discuss the existing evidence and hypotheses about the pathophysiology of both conditions.
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Belhassine et al. (2018) conducted a case report in Gastric adenocarcinoma with pulmonary lymphangitic carcinomatosis and pulmonary tumour thrombotic microangiopathy (n=1). A young Chinese woman presented with gastric adenocarcinoma revealed by atypical radiographic lesions consistent with both pulmonary lymphangitic carcinomatosis and pulmonary tumour thrombotic microangiopathy.
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