Key result
Metastatic lung adenocarcinoma with pulmonary lymphangitic carcinomatosis portends a poor prognosis in a 64-year-old smoker.
Case Report (n=1)
Describes the mechanism of pulmonary lymphangitic carcinomatosis in metastatic adenocarcinoma of the lung.
Hypothesis-generating for spread patterns in pulmonary lymphangitic carcinomatosis; leaves open validation in larger cohorts before diagnostic impact.
Pulmonary lymphangitic carcinomatosis (PLC) is part of the spectrum of metastatic disease. Most cases result from dissemination of adenocarcinomas. Micro hematogenous spread to the periphery of the lung, with subsequent retrograde, centripetal lymphatic extension toward the hilar region, is the responsible mechanism in approximately 75% of patients.
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Somaya Albhaisi (2016) conducted a case report in Pulmonary Lymphangitic Carcinomatosis due to Metastatic Adenocarcinoma of the Lung (n=1). Chemotherapy (carboplatin and pemetrexed) was evaluated on Clinical outcome. A 64-year-old male with a long history of smoking presented with metastatic lung adenocarcinoma associated with the radiological finding of pulmonary lymphangitic carcinomatosis and a poor prognosis.
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