Why the study?
Pulmonary lymphangitis carcinomatosis is a life-threatening complication of malignancies where misleading and nonspecific symptoms frequently delay diagnosis, prompting a review of its epidemiology, clinical manifestations, and survival.
What are the epidemiology, clinical manifestations, and survival outcomes of patients with pulmonary lymphangitis carcinomatosis?
Population
139 individual patient cases from 108 articles with pulmonary lymphangitis carcinomatosis
Design
Systematic review and meta-analysis of case reports and case series
Authors
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Prompts early palliative referral in cancer patients with new dyspnea; confirms the aggressive prognosis of pulmonary lymphangitis carcinomatosis.
What are the epidemiology, clinical manifestations, and survival outcomes of patients with pulmonary lymphangitis carcinomatosis?
Pulmonary lymphangitis carcinomatosis is a rare, life-threatening complication of malignancies, most commonly breast, lung, and gastric cancers, characterized by a very poor prognosis with rapid mortality after symptom onset.
Monika Klimek (2019) studied this question.
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