Drug - Drug Interaction: An Important Drug Related Problem

Drug interaction is defined as the clinical or pharmacological response occurs when two drugs administered simultaneously, results in beneficial or harmful effects in a person. Based upon mechanism of action drug interactions are classified in to three typ interactions, and Pharmaceutical interactions. Based upon severity, drug interactions are classified in to four types: Minor, moderate, major and contraindicated. According to WHO drug interactions are main cause of mortality and morbidity. It has been estimated that prevalence of interactions is estimated to be 1 22% in world. Drug-drug interactions accounted for 1.1% hospital admissions and 0.1% hospital visits.