Study on Drug Releasing Behaviour of Different Biopolymers

Biopolymers play an important role in controlling drug release from various drug delivery systems. done to identify their drug releasing pattern based on previously published articles since 1990.Both research and review articles are selected which discuss about various drug delivery systems which shows extended drug release behaviour of different biopolymer. Guar gum is a hydrophilic polymer, which on exposure to aqueous fluid, gets hydrated and form viscous gel layer which further retards drug release. Xanthan gum being an anionicpolymer, following exposure to an acidic media will impede ge of drug. Chitosan shows pH dependant solubility. is more commonly used for gastric delivery of drugs. The hydration property of Sodium alginate is r for modifying drug release at different pH values. Mucoadhesive property of Hyaluronic acid(HA) is very well utilised in various drug delivery systems. Carrageenan being an anionic polymer, undergo ionic interactions, which resulted in favorable increases in the water uptake capacity and gel viscosity, leading to over the drug release. The drug release from Polycaprolactone (PCL) based drug delivery system can be accelerated by reducing crystalline nature phasic drug release; that is initial diffusion, matrix hydration and degradation. The self crosslinked hydrogel is utilised for controlled drug delivery. The side chain functional group of pectin with nasal mucosal tissues enabling its utility in nasal drug delivery. potential for the development of new, advanced, safe and efficient drug delivery system. biopolymers evaluated for biodegradation and extended drug release, PCL is identified as the best.