Key result
Coronary heart disease and aging independently impaired functional capacity during maximal exercise, with coronary disease reducing maximal duration, heart rate, and systolic pressure.
Why the study?
How do aging and coronary heart disease independently affect submaximal and maximal exercise capacity?
Population
296 men, comprising 117 coronary patients, 117 age-matched healthy middle-aged men, and 62 healthy young men.
Comparison
Multistage treadmill test of maximal exercise vs Healthy young men and healthy middle-aged men
Design
Cross-sectional
Authors
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Supports accounting for age and CHD in exercise test interpretation; leaves open prognostic value and causal mechanisms.
Cross-Sectional (n=296)
How do aging and coronary heart disease independently affect submaximal and maximal exercise capacity?
Coronary heart disease and aging independently impair maximal exercise capacity, with CHD specifically reducing maximal systolic pressure and heart rate reserve while increasing submaximal heart rate stress and ischemic S-T depression.
Kasser et al. (1969) conducted a cross-sectional in Coronary heart disease (n=296). Coronary heart disease and aging vs. Healthy young and middle-aged men was evaluated on Functional capacity (duration of exertion, maximal heart rate, maximal systolic pressure). Coronary heart disease and aging independently impaired functional capacity during maximal exercise, with coronary disease reducing maximal duration, heart rate, and systolic pressure.
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