Key result
Exposure to a cold environment (15°C vs 25°C) significantly increased mean systemic arterial pressure during exercise (110 vs 92 mm Hg; p<0.001) and total peripheral resistance.
Why the study?
Does exposure to a cold environment alter circulatory responses at rest and during exercise in patients with and without coronary artery disease?
Does exposure to a cold environment alter circulatory responses at rest and during exercise in patients with and without coronary artery disease?
Absolute Event Rate: 110% vs 92%
p-value: p=<0.001
Cold exposure increases peripheral resistance and arterial pressure, which augments myocardial oxygen demand and provides a physiological basis for cold-induced angina.
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May increase myocardial oxygen demand during cold exercise; leaves open whether this triggers angina in CAD.
Epstein et al. (1969) studied Coronary-artery disease (n=11). Reduction in environmental temperature (15°C) vs. 25°C environmental temperature was evaluated on Mean systemic arterial pressure during exercise (mm Hg) (p=<0.001). Exposure to a cold environment (15°C vs 25°C) significantly increased mean systemic arterial pressure during exercise (110 vs 92 mm Hg; p<0.001) and total peripheral resistance.
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