Key result
Transthoracic Doppler echocardiography differentiated TIMI 3 from TIMI ≤2 coronary reperfusion with 77% sensitivity and 94% specificity using a diastolic peak distal LAD flow velocity ≥25 cm/s.
Why the study?
Can transthoracic Doppler echocardiography (TTDE) differentiate TIMI grade 3 from TIMI grade ≤2 coronary reperfusion in patients with anterior acute myocardial infarction before emergent coronary intervention?
Population
46 consecutive patients with a first anterior acute myocardial infarction in the acute phase before emergent…
Comparison
Transthoracic Doppler echocardiography to… vs Coronary angiography performed 29±12 minutes later
Design
Cross-sectional
Follow-up
29±12 minutes (time to angiography)
Authors
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May support noninvasive reperfusion assessment in anterior AMI; leaves open prospective validation before clinical adoption.
Observational (n=46)
Can transthoracic Doppler echocardiography (TTDE) differentiate TIMI grade 3 from TIMI grade ≤2 coronary reperfusion in patients with anterior acute myocardial infarction before emergent coronary intervention?
Absolute Event Rate: 40% vs 20%
p-value: p=<0.0001
TTDE can accurately and noninvasively identify TIMI 3 coronary reperfusion in patients with anterior AMI prior to emergent coronary intervention.
Lee et al. (2003) conducted an observational in anterior acute myocardial infarction (n=46). Transthoracic Doppler echocardiography (TTDE) vs. Coronary angiography (TIMI grades) was evaluated on Peak distal LAD flow velocity in patients with TIMI 3 compared with TIMI 2 (p=<0.0001). Transthoracic Doppler echocardiography differentiated TIMI 3 from TIMI ≤2 coronary reperfusion with 77% sensitivity and 94% specificity using a diastolic peak distal LAD flow velocity ≥25 cm/s.
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