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August 1, 1995Journal of VirologyOpen Access

Lower in vivo mutation rate of human immunodeficiency virus type 1 than that predicted from the fidelity of purified reverse transcriptase

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Authors

LMLouis M. ManskyUniversity of MinnesotaHTHoward M. TeminCalifornia Institute of Technology

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Mansky et al. (1995) studied this question.

synapsesocial.com/papers/6a1ff9ea2065d284090dbce3https://doi.org/10.1128/jvi.69.8.5087-5094.1995
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Also Consider

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  1. 1Broad spectrum of in vivo forward mutations, hypermutations, and mutational hotspots in a retroviral shuttle vector after a single replication cycle: substitutions, frameshifts, and hypermutations.1990 · 280 citations
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  3. 3Packaging system for rapid production of murine leukemia virus vectors with variable tropism1992 · 258 citations
  4. 4Human immunodeficiency virus type 1 Pr55gag and Pr160gag-pol expressed from a simian virus 40 late replacement vector are efficiently processed and assembled into viruslike particles1990 · 182 citations
  5. 5Retrovirus variation and reverse transcription: abnormal strand transfers result in retrovirus genetic variation.1993 · 310 citations