Key result
Ischemic preconditioning significantly reduced the incidence of ventricular fibrillation after declamping compared to control (48.8% vs 79.1%, P=0.004) in patients undergoing CABG.
Why the study?
Does ischemic preconditioning reduce postoperative ventricular tachyarrhythmias in patients undergoing CABG with 3-vessel disease?
Population
86 patients undergoing CABG with stable and unstable 3-vessel disease
Comparison
Ischemic preconditioning vs Control group (no ischemic preconditioning)
Design
RCT, equally randomly assigned
Follow-up
24 hours
Authors
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Supports ischemic preconditioning in CABG; extends evidence to reduced postoperative ventricular tachyarrhythmias.
RCT (n=86)
Equally randomly assigned
Does ischemic preconditioning reduce postoperative ventricular tachyarrhythmias in patients undergoing CABG with 3-vessel disease?
Absolute Event Rate: 48.8% vs 79.1%
p-value: p=0.004
Ischemic preconditioning during CABG significantly reduces postoperative ventricular tachyarrhythmias, mechanical ventilation time, and inotrope requirement.
Wu et al. (2002) conducted an RCT in CABG with stable and unstable 3-vessel disease (n=86). Ischemic preconditioning vs. Control was evaluated on Ventricular fibrillation after declamping (p=0.004). Ischemic preconditioning significantly reduced the incidence of ventricular fibrillation after declamping compared to control (48.8% vs 79.1%, P=0.004) in patients undergoing CABG.
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