Key result
Underlying myocardial infarction was associated with a significantly higher 3-year all-cause mortality compared to nonischemic cardiomyopathy in Japanese patients with chronic heart failure (29.0% vs 12.4%).
Why the study?
Does underlying myocardial infarction worsen prognosis compared to nonischemic cardiomyopathy in Japanese patients with chronic heart failure?
Population
593 Japanese patients with chronic heart failure from the CHART registry, including 283 with myocardial…
Comparison
Myocardial infarction as the underlying etiology… vs Nonischemic cardiomyopathy as the underlying…
Design
Cohort
Follow-up
mean 1.9±0.9 years
Authors
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Prior MI was associated with higher mortality in Japanese chronic HF; leaves open whether etiology-specific strategies improve outcomes.
Cohort (n=593)
Yes
Does underlying myocardial infarction worsen prognosis compared to nonischemic cardiomyopathy in Japanese patients with chronic heart failure?
Absolute Event Rate: 29% vs 12.4%
p-value: p=<0.0005
Japanese patients with chronic heart failure following myocardial infarction have a significantly worse prognosis than those with nonischemic cardiomyopathy, particularly among those with preserved ejection fraction or mild symptoms.
Shiba et al. (2005) conducted a cohort in Chronic Heart Failure (n=593). Underlying myocardial infarction vs. Nonischemic cardiomyopathy was evaluated on 3-year all-cause mortality (p=<0.0005). Underlying myocardial infarction was associated with a significantly higher 3-year all-cause mortality compared to nonischemic cardiomyopathy in Japanese patients with chronic heart failure (29.0% vs 12.4%).
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