Key result
Preoperative heparin use or heparin sensitivity index < 1.3 (RR ~2) and LAD thromboendarterectomy (RR ~5.5) were independent risk factors for fatal myocardial infarction after coronary surgery.
Why the study?
What are the independent risk factors for fatal myocardial infarction after coronary bypass graft surgery?
Population
1561 consecutive patients who underwent coronary revascularization during a 10-month period
Comparison
Preoperative use of subcutaneous/intravenous… vs Patients without these risk factors
Design
Cohort
Follow-up
Perioperative period
Authors
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May warrant heightened perioperative vigilance in CABG; hypothesis-generating and requires prospective validation before practice change.
Cohort (n=1,561)
What are the independent risk factors for fatal myocardial infarction after coronary bypass graft surgery?
Effect estimate: RR ~2 for heparin use/sensitivity < 1.3; RR ~5.5 for LAD thromboendarterectomy
Preoperative heparin use, heparin resistance, and LAD thromboendarterectomy are significant independent risk factors for fatal perioperative myocardial infarction in patients undergoing CABG.
Ranucci et al. (2001) conducted a cohort in Coronary artery bypass graft surgery (n=1,561). Preoperative heparin use, heparin sensitivity index < 1.3, and LAD thromboendarterectomy vs. Patients without these risk factors was evaluated on Fatal myocardial infarction (RR ~2 for heparin use/sensitivity < 1.3; RR ~5.5 for LAD thromboendarterectomy). Preoperative heparin use or heparin sensitivity index < 1.3 (RR ~2) and LAD thromboendarterectomy (RR ~5.5) were independent risk factors for fatal myocardial infarction after coronary surgery.
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