Key result
C-terminal basic residues in cardiac troponin T are critical for regulating cardiac muscle contraction by providing full inhibition and limiting activation by calcium.
Population
Cardiac muscle/troponin T model
Design
Preclinical
Authors
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May warrant caution before clinical translation; leaves open validation in human cardiac models.
C-terminal basic residues in cardiac troponin T play a critical role in regulating cardiac muscle contraction and limiting activation by calcium.
Johnson et al. (2019) studied this question. C-terminal basic residues in cardiac troponin T are critical for regulating cardiac muscle contraction by providing full inhibition and limiting activation by calcium.
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