Key result
Active orthostatism reduced overall baroreflex gain from 23.7 to 10.0 ms/mmHg, selectively reducing the cardiopulmonary component from 18.5 to 4.8 ms/mmHg without changing the arterial component.
Observational (n=30)
Absolute Event Rate: 10% vs 23.7%
A trivariate autoregressive model incorporating respiration can successfully separate overall baroreflex gain into arterial and cardiopulmonary components, revealing that only the cardiopulmonary component is reduced by active orthostatism.
No takes yet. Share an insight, caveat, or question.
Active orthostatism selectively impairs cardiopulmonary baroreflex gain; hypothesis-generating for component separation and leaves clinical relevance open.
Lucini et al. (2000) conducted an observational in Healthy subjects (n=30). Active orthostatism (standing) vs. Rest was evaluated on Overall baroreflex gain (alphalumped). Active orthostatism reduced overall baroreflex gain from 23.7 to 10.0 ms/mmHg, selectively reducing the cardiopulmonary component from 18.5 to 4.8 ms/mmHg without changing the arterial component.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: