Humanized monoclonal antibodies to tumor necrosis factor- alpha are valuable for the treatment of rheumatologic conditions, but they have been associated with the development of serious infections. We report the first 2 cases of leprosy developing after treatment with infliximab. After discontinuation of infliximab, both patients developed type 1 ("reversal") leprosy reactions.
No takes yet. Share an insight, caveat, or question.
Scollard et al. (2006) studied this question.
Synapse has enriched one closely related paper. Consider it for comparative context: