Key result
Treadmill testing in 410 normal subjects showed the cardiac chronotropic response follows a linear function (%HRR = 0.95 × %MR + 3.4 for Bruce protocol), independent of the exercise protocol.
Population
410 normal subjects without evidence of medical illness or cardiac medications
Design
Cross-sectional
Authors
Loading...
May aid chronotropic assessment during treadmill testing in normals; leaves open prospective validation in clinical cohorts.
Observational (n=410)
The normal cardiac chronotropic response to exercise can be accurately modeled as a simple linear mathematical function independent of the treadmill protocol used.
Wilkoff et al. (1989) conducted an observational in Normal subjects (n=410). Treadmill testing was evaluated on Cardiac chronotropic response to exercise. Treadmill testing in 410 normal subjects showed the cardiac chronotropic response follows a linear function (%HRR = 0.95 × %MR + 3.4 for Bruce protocol), independent of the exercise protocol.