Key result
Preload responsiveness to passive leg raising was not significantly different between healthy pregnant women at 22-24 weeks of gestation and non-pregnant controls (14.8% vs 18.5%, p=0.705).
Why the study?
Does passive leg raising alter systemic hemodynamics differently in healthy pregnant women at 22-24 weeks of gestation compared to non-pregnant controls?
Population
162 women, comprising 108 healthy low-risk pregnant women at 22-24 weeks of gestation and 54 healthy…
Comparison
Passive leg raising obtained by rapidly lowering… vs Baseline measurements taken after 10 minutes of…
Design
Cross-sectional
Follow-up
90 seconds
Authors
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Suggests preserved preload reserve in mid-pregnancy; extends normal hemodynamic data but leaves open applicability to later gestation or complications.
Cross-Sectional (n=162)
No
Does passive leg raising alter systemic hemodynamics differently in healthy pregnant women at 22-24 weeks of gestation compared to non-pregnant controls?
Absolute Event Rate: 14.8% vs 18.5%
p-value: p=0.705
The physiological hemodynamic response to passive leg raising is similar between healthy pregnant women at 22-24 weeks of gestation and non-pregnant women, indicating that normal preload reserve is preserved in mid-pregnancy.
Vårtun et al. (2014) conducted a cross-sectional in Healthy pregnancy (n=162). Passive leg raising vs. Non-pregnant controls was evaluated on Preload responsiveness (>10% increase in stroke volume or cardiac output after passive leg raising) (p=0.705). Preload responsiveness to passive leg raising was not significantly different between healthy pregnant women at 22-24 weeks of gestation and non-pregnant controls (14.8% vs 18.5%, p=0.705).
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