Key result
Normal pregnancy was associated with a 29% increase in the ventriculo-arterial coupling index compared to 6 months postpartum (P<0.01), indicating a decrease in LV function.
Why the study?
Does normal pregnancy alter systemic arterial properties and ventriculo-arterial interaction compared to the postpartum state in healthy women?
Observational (n=65)
Does normal pregnancy alter systemic arterial properties and ventriculo-arterial interaction compared to the postpartum state in healthy women?
Effect estimate: 29% increase
p-value: p=< 0.01
Normal pregnancy is associated with an increased ventriculo-arterial coupling index, suggesting a decrease in LV function that is not fully compensated by vascular adaptation.
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Does not support altering care in healthy pregnancies; leaves open whether transient LV changes predict future cardiovascular risk.
Estensen et al. (2012) conducted an observational in Normal pregnancy (n=65). Normal pregnancy vs. 6 months postpartum was evaluated on Ventriculo-arterial coupling index (E(a)I/E(LV)I) (29% increase, p=< 0.01). Normal pregnancy was associated with a 29% increase in the ventriculo-arterial coupling index compared to 6 months postpartum (P<0.01), indicating a decrease in LV function.
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