Key result
Nifedipine induced a significant afterload reduction and compensatory increase in cardiac output in normotensive pregnant women, without influencing uteroplacental and fetal circulations.
Why the study?
Does nifedipine 20 mg alter maternal and fetal haemodynamics in normotensive pregnant women?
Population
15 normotensive pregnant women
Design
Cohort
Authors
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Reassures on nifedipine hemodynamic safety in normotensive pregnancy; leaves open effects in hypertensive cohorts.
Observational (n=15)
Does nifedipine 20 mg alter maternal and fetal haemodynamics in normotensive pregnant women?
In normotensive pregnant women, 20 mg of nifedipine safely reduces maternal afterload and increases cardiac output without adversely affecting uteroplacental or fetal circulations.
Cornette et al. (2010) conducted an observational in Normotensive pregnancy (n=15). Nifedipine was evaluated on Maternal and fetal haemodynamic effects. Nifedipine induced a significant afterload reduction and compensatory increase in cardiac output in normotensive pregnant women, without influencing uteroplacental and fetal circulations.
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