Why the study?
Does filtered P wave duration dispersion measured by P-SAECG after a single dose of disopyramide predict its long-term efficacy in preventing paroxysmal atrial fibrillation?
Population
32 patients with symptomatic paroxysmal atrial fibrillation (PAF) and 31 healthy volunteers (total n=63).
Comparison
Disopyramide evaluated using P wave… vs Healthy volunteers and internal comparison…
Design
Cohort
Follow-up
4 weeks and 6 months
Authors
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P-SAECG dispersion change after disopyramide may predict long-term response in paroxysmal AF; leaves open prospective validation before clinical use.
Does filtered P wave duration dispersion measured by P-SAECG after a single dose of disopyramide predict its long-term efficacy in preventing paroxysmal atrial fibrillation?
Measuring filtered P wave duration dispersion via P-SAECG 3 hours after a single dose of disopyramide can accurately predict the drug's long-term efficacy in suppressing paroxysmal atrial fibrillation.
Kubara et al. (1999) studied this question.
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