Key result
Goal-oriented hemodynamic therapy significantly reduced mechanical ventilator time (10.48 vs 16.43 hours) and duration of inotrope use (23.2 vs 39.12 hours) compared to standard care in patients undergoing cardiac surgery.
Why the study?
Does goal oriented hemodynamic therapy improve early post-operative outcomes in adult patients undergoing cardiac surgery?
Population
n=100 adult patients undergoing cardiac surgery in a tertiary level teaching hospital
Comparison
Goal oriented hemodynamic therapy using FloTrac… vs Standard postoperative monitoring
Design
RCT, prospective randomized
Follow-up
early post-operative period
Authors
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Supports goal-oriented hemodynamic therapy after cardiac surgery; extends RCT evidence for optimized perioperative management.
RCT (n=100)
Open-label
Sealed envelope technique
No
Does goal oriented hemodynamic therapy improve early post-operative outcomes in adult patients undergoing cardiac surgery?
Mean Difference: -5.949 (95% CI -11.64–-0.254)
Absolute Event Rate: 10.48% vs 16.429%
p-value: p=0.041
Goal-oriented hemodynamic therapy in the early postoperative period significantly reduces ventilator time and inotrope duration in cardiac surgery patients.
Shrestha et al. (2015) conducted an RCT in Cardiac surgery (n=100). Goal oriented hemodynamic therapy (FloTrac device) vs. Standard postoperative monitoring was evaluated on Ventilator time (hours) (95% CI -11.64 to -0.254, p=0.041). Goal-oriented hemodynamic therapy significantly reduced mechanical ventilator time (10.48 vs 16.43 hours) and duration of inotrope use (23.2 vs 39.12 hours) compared to standard care in patients undergoing cardiac surgery.
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