Key result
Insulin-like growth factor-binding proteins (IGFBPs) function to modulate IGF actions, facilitate IGF storage in extracellular matrices, and exert IGF effects on target cells.
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IGFBP functions in IGF modulation are summarized; leaves open targeted cardiovascular studies before clinical adoption.
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Rajaram et al. (1997) studied this question. Insulin-like growth factor-binding proteins (IGFBPs) function to modulate IGF actions, facilitate IGF storage in extracellular matrices, and exert IGF effects on target cells.
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