Key result
Critical circulation and age older than 70, especially when requiring dopamine support, were identified as the main risk factors for serious acute renal failure following open heart surgery.
Why the study?
What preoperative, peroperative, and postoperative variables predict the development of serious acute renal failure following open heart surgery?
Observational
What preoperative, peroperative, and postoperative variables predict the development of serious acute renal failure following open heart surgery?
Critical circulation and the need for dopamine support, particularly in patients older than 70, are major risk factors for developing serious acute renal failure after open heart surgery.
May inform closer renal monitoring in high-risk patients; leaves open prospective validation and preventive trials.
The influence of 51 preoperative, peroperative and postoperative variables on the development of serious acute renal failure (ARF) following open heart surgery was studied. Although a large number of significant variables was found, a logit-model with only 2 explanatory variables showed an almost perfect fit. With this model the chances of serious ARF up to 90% were estimated. The results suggest that a critical circulation is the main cause of serious ARF. Furthermore, a reduced ability to cope with a critical circulation without renal failure plays an important role in the pathogenesis. There is a higher risk of serious ARF for patients older than 70, especially when circulatory support with dopamine is needed.
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Hc et al. (1985) conducted an observational in Serious acute renal failure following open heart surgery. Preoperative, peroperative and postoperative variables (including critical circulation, age >70, and dopamine support) was evaluated on Development of serious acute renal failure (ARF). Critical circulation and age older than 70, especially when requiring dopamine support, were identified as the main risk factors for serious acute renal failure following open heart surgery.
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