Key result
Acute postoperative renal failure linked to ~9-fold higher mortality after open cardiac surgery.
Why the study?
The incidence, risk factors, and outcomes of acute renal failure after open cardiac surgery in patients with normal preoperative renal function were not well characterized.
Does acute postoperative renal failure increase mortality in patients with normal preoperative renal function undergoing open cardiac surgery?
Population
302 patients undergoing open heart surgery with normal preoperative renal function
Comparison
Acute postoperative renal failure (creatinine >1.5 mg·dL(-1)) vs no acute postoperative renal failure (creatinine ≤1.5 mg·dL(-1))
Design
Prospective case-control analysis
Follow-up
Postoperative period
Authors
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Postoperative renal failure marks high mortality risk despite normal baseline function; leaves open whether prevention reduces deaths.
Case-Control (n=302)
Does acute postoperative renal failure increase mortality in patients with normal preoperative renal function undergoing open cardiac surgery?
Absolute Event Rate: 18.8% vs 2.1%
Acute renal failure after open cardiac surgery in patients with normal preoperative renal function is uncommon (1.2%) but is associated with a significantly increased mortality rate.
Hashemzadeh et al. (2012) conducted a case-control in Open cardiac surgery (n=302). Acute postoperative renal failure vs. No acute postoperative renal failure (creatinine ≤1.5 mg/dL) was evaluated on Postoperative mortality. Acute postoperative renal failure after open cardiac surgery was associated with significantly higher postoperative mortality compared to patients without renal failure (18.8% vs 2.1%).
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