Key result
Initial ST-segment elevation in patients with acute myocardial infarction due to unprotected left main coronary artery disease was an independent predictor of in-hospital mortality (OR 2.37) compared to NSTEMI.
Why the study?
Does STEMI presentation compared to NSTEMI presentation predict higher mortality in patients with acute MI due to unprotected left main coronary artery disease?
Observational (n=643)
Yes
Does STEMI presentation compared to NSTEMI presentation predict higher mortality in patients with acute MI due to unprotected left main coronary artery disease?
Odds Ratio: 2.37 (95% CI 1.14–4.91)
Absolute Event Rate: 27.2% vs 10.4%
p-value: p=0.02
In patients with acute MI due to unprotected left main coronary artery disease, STEMI presentation is an independent predictor of higher in-hospital and 12-month mortality compared to NSTEMI, with no significant gender-related differences in mortality.
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May prompt closer monitoring in STEMI left main AMI; leaves open prospective validation of risk-stratified strategies.
Sadowski et al. (2015) conducted an observational in Acute myocardial infarction due to unprotected left main coronary artery disease (n=643). ST-segment elevation (STEMI) vs. Non-ST-segment elevation (NSTEMI) was evaluated on In-hospital mortality (OR 2.37, 95% CI 1.14-4.91, p=0.02). Initial ST-segment elevation in patients with acute myocardial infarction due to unprotected left main coronary artery disease was an independent predictor of in-hospital mortality (OR 2.37) compared to NSTEMI.
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