The influence of gender differences on the results of treatment of acute myocardial infarction with elevated ST segment (the hospital period)

Aim. To evaluate the effect of gender on mortality from acute myocardial infarction with elevated ST segment (STEMI). Materials and methods. In this single-centre retrospective study, we analyzed outcomes of the in-hospital stage of the treatment of 553 men (67,7%) and 263 women (32.3%). 160 women (60,8%) underwent primary percutaneous coronary intervention (pPCI) and 103 pharmacoinvasive strategy (FAST-PCI), (39,2%). The same treatment was given to 295 (53,3%) and 258 (46,7%) men respectively. Patients with “primary medical contact (PMC) - balloon” of less than 60 minutes and “PMC - balloon” symptom” of more than 6 hours were excluded from the study. For the majority of the patients this time interval was on the order of 120 minutes. Results. Mortality in women was significantly higher than in men regardless of the reperfusion strategy: total 15.3 percent (18.1 percent in case of PCCW and 10.9% in case of FIS) in women and 3.1% (5.1% in case of PCCW and 0.8% in case of FIS) in men (p < 0.001). The probability of a lethal outcome in women was 4 times higher (OR 4,4 DI 95% 2,7-7,1).