Key result
Relief of hypoxia via oxygen administration or surgery significantly increased small-bowel xylose absorption by a mean of 11.7%.
Why the study?
Does relief of hypoxia improve small-bowel absorption in patients with arterial oxygen desaturation?
Observational (n=16)
Does relief of hypoxia improve small-bowel absorption in patients with arterial oxygen desaturation?
Mean Difference: 11.7
p-value: p=significant
Relief of hypoxia significantly improves small-bowel absorption in patients with arterial oxygen desaturation due to congenital heart disease or chronic lung disease.
Small-bowel absorption was studied using the xylose absorption test in 16 patients with varying degrees of arterial oxygen desaturation due to either congenital heart disease or chronic lung disease. Xylose absorption was decreased in the cases with more severe desaturation. The correlation of xylose absorption with arterial saturation was significant. In nine cases hypoxia was relieved by either oxygen administration or surgery. Repeat testing showed an increase in xylose absorption in every case, the mean increase being 11.7%, which was statistically significant.
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James S. Milledge (1972) conducted an observational in Arterial oxygen desaturation due to congenital heart disease or chronic lung disease (n=16). Relief of hypoxia (oxygen administration or surgery) vs. Baseline (prior to relief of hypoxia) was evaluated on Xylose absorption (mean increase 11.7%, p=significant). Relief of hypoxia via oxygen administration or surgery significantly increased small-bowel xylose absorption by a mean of 11.7%.
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