Population
Rodent muscle cDNA clone libraries, and differentiated cultures of rat L6 and mouse C2 muscle cell lines
Design
Preclinical
Authors
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No clinical implications for troponin testing; leaves open nerve-independent isoform regulation in skeletal muscle research models.
The study demonstrates that the differential expression of skeletal muscle troponin I isoforms is governed by gene regulatory mechanisms controlling specific mRNA abundances, which can occur independently of neuronal input.
Koppe et al. (1989) studied this question.
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