Key result
Type 2 diabetes is linked to prolonged arrhythmogenicity markers including a ~10 ms longer Tp-e interval.
Why the study?
Cardiovascular disease is the most common complication of DM and arrhythmia risk is increased, prompting evaluation of the correlation of electrocardiographic arrhythmogenicity markers with HbA1c and fasting blood glucose.
Cross-Sectional (n=153)
No
Absolute Event Rate: 88% vs 78%
p-value: p=<0.001
Electrocardiographic arrhythmogenicity markers (QTc, Tp-e, Tp-e/QTc) are significantly prolonged in patients with type 2 diabetes and correlate with HbA1c, suggesting a potential non-invasive method to assess arrhythmia risk.
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Cem Onur Kıraç (2023) conducted a cross-sectional in Type 2 diabetes mellitus (n=153). Type 2 diabetes mellitus vs. Healthy individuals was evaluated on Tp-e interval (ms) (p=<0.001). Type 2 diabetes mellitus was associated with significantly prolonged electrocardiographic arrhythmogenicity markers, including the Tp-e interval (88 vs 78 ms, p<0.001), compared to healthy controls.
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