Population
Escherichia coli synthesizing three splice variants of the Gs alpha subunit using recombinant DNA techniques
Design
Preclinical
Authors
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Challenges one-G-protein-one-effector model; leaves open in vivo roles and human relevance.
A single G protein alpha subunit splice variant can regulate more than one effector function, specifically both adenylyl cyclase and calcium channels.
Mattera et al. (1989) studied this question.
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