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August 1, 1975Circulation ResearchOpen Access

The sequence of retrograde atrial activation in the canine heart. Correlation with positive and negative retrograde P waves.

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Population

Canine heart model

Design

Preclinical

Authors

AWAlbert L. WaldoElectrophysiologyKVKari J. VitikainenNewYork–Presbyterian HospitalBHB F HoffmanColumbia University

Discussion

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Implication

Should not yet alter clinical P-wave interpretation; leaves open validation in human atrial conduction studies.

Structured PICO

P
Population
Canine heart model
I
Intervention
Atrial pacing from the region of the sinus node, posterior-inferior left atrium, right ventricular epicardium, and sites anterior/posterior to the coronary sinus ostium
O
Outcome
P-wave polarity and morphology in leads II, III, and aVF and sequence of atrial activationsurrogate

The relative timing of impulse arrival at Bachmann's bundle versus the posterior left atrium determines P-wave polarity and morphology during retrograde atrial activation in canine hearts.

Cite This Study

Waldo et al. (1975) studied this question.

synapsesocial.com/papers/6a2039ea5a40e2199cd8e426https://doi.org/10.1161/01.res.37.2.156
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Manner of Stimulus Conduction in Atria1967 · 9 citations
  2. 2IV. CORONARY SINUS RHYTHM1931 · 25 citations
  3. 3The P Wave and P-R Interval1970 · 91 citations
  4. 4Electrical Potential Distribution Surrounding the Atria during Depolarization and Repolarization in the Dog1969 · 100 citations
  5. 5An experimental evaluation of continuous normothermic, intermittent hypothermic, and intermittent normothermic coronary perfusion1974 · 21 citations