Key result
Carotid endarterectomy significantly increased collagen-induced platelet aggregation (p<0.01) and decreased adrenalin-induced aggregation (p<0.01) in the early postoperative stage.
Why the study?
Does the type of perioperative antithrombotic therapy affect chronological changes in platelet aggregation in patients undergoing carotid endarterectomy?
Observational (n=94)
No
Does the type of perioperative antithrombotic therapy affect chronological changes in platelet aggregation in patients undergoing carotid endarterectomy?
Following carotid endarterectomy, collagen-induced platelet aggregation is elevated for about a week due to exposure of the medial collagen layer, suggesting a hyperaggregable state that may be mitigated by antiplatelet therapy.
Answers are grounded in this paper and cite their sources.
Suggests transient post-CEA hyperaggregability; leaves open whether antithrombotic regimen modulates aggregation changes.
No abstract yet. The journal hasn't published one we can show.
No takes yet. Share an insight, caveat, or question.
Asano et al. (1995) conducted an observational in Carotid stenosis (n=94). Carotid endarterectomy vs. Preoperative baseline and brain tumor surgery controls was evaluated on Collagen-induced platelet aggregation after carotid endarterectomy (p=<0.01). Carotid endarterectomy significantly increased collagen-induced platelet aggregation (p<0.01) and decreased adrenalin-induced aggregation (p<0.01) in the early postoperative stage.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: