Key result
Higher preoperative platelet aggregation is linked to periprocedural ischemic events after carotid artery stenting.
Why the study?
The relationship between preoperative platelet aggregation and perioperative ischemic complications after cervical internal carotid artery stenting was unclear.
Does preoperative platelet aggregation analysis predict perioperative complications in patients undergoing carotid artery stenting?
Observational (n=18)
No
Does preoperative platelet aggregation analysis predict perioperative complications in patients undergoing carotid artery stenting?
High preoperative platelet aggregation rates for ADP and collagen may be associated with an increased risk of perioperative ischemic complications during carotid artery stenting.
Answers are grounded in this paper and cite their sources.
Elevated preoperative platelet aggregation may flag higher ischemic risk after carotid stenting; leaves open whether testing should guide therapy in larger studies.
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Enomoto et al. (2008) conducted an observational in Carotid artery stenosis (n=18). Preoperative platelet aggregation vs. Patients without ischemic events was evaluated on Maximum platelet aggregation rate (collagen 2.0 µg/ml) in patients with vs without periprocedural ischemic events (p=<0.05). Preoperative maximum platelet aggregation rates in response to collagen and ADP were significantly higher in patients who developed periprocedural ischemic events after carotid artery stenting.
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