Key result
CMR provides diagnostic and prognostic value for detecting and risk-stratifying arrhythmogenic substrates in systemic autoimmunity.
Why the study?
Cardiac rhythm disturbances, specifically ventricular arrhythmias, can worsen the prognosis of patients with systemic autoimmunity, highlighting the need to evaluate CMR for detecting and risk-stratifying arrhythmogenic substrates.
CMR is a valuable non-invasive imaging modality for the detection and risk stratification of arrhythmogenic substrates in patients with systemic autoimmunity.
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CMR may aid arrhythmia risk assessment in systemic autoimmunity; leaves open need for prospective outcome trials.
Patients with systemic autoimmunity due to autoimmune rheumatic diseases (ARDs) or sarcoidosis frequently present with systemic manifestations including cardiac involvement. Cardiac rhythm disturbances and specifically ventricular arrhythmias (VAs) may affect the prognosis of these patients. Cardiovascular magnetic resonance imaging (CMR) is a non-invasive imaging modality that can provide valuable diagnostic and prognostic information in patients with ARDs or systemic autoimmunity in general. In this narrative review, we briefly present the underlying pathophysiologic mechanisms contributing to arrhythmogenicity in patients with systemic autoimmunity. Furthermore, we discuss recent advances underlying the role and value of CMR for use in the detection and risk stratification of arrhythmogenic substrates in patients with systemic autoimmunity and VAs.
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Markousis‐Mavrogenis et al. (2023) conducted a review in Systemic autoimmunity and ventricular arrhythmias. Cardiovascular Magnetic Resonance (CMR) was evaluated. Cardiovascular magnetic resonance imaging provides valuable diagnostic and prognostic information for detecting and risk-stratifying arrhythmogenic substrates in patients with systemic autoimmunity.
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