Key result
The presence of late potentials on signal-averaged ECG identified patients at a higher risk for sudden death or recurrent sustained ventricular tachycardia (overall 21% vs 1.6% without late potentials).
Why the study?
Does the signal-averaged ECG predict sudden death or recurrent sustained ventricular tachycardia in patients with suspected malignant ventricular arrhythmias?
Population
517 patients in whom there was a suspicion for malignant ventricular arrhythmias
Comparison
Signal-averaged ECG to detect late potentials… vs Absence of late potentials, or no EP-guided…
Design
Cohort
Authors
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Late potentials on signal-averaged ECG were associated with higher sudden death or VT risk; leaves open prospective validation before guiding therapy.
Cohort (n=517)
Does the signal-averaged ECG predict sudden death or recurrent sustained ventricular tachycardia in patients with suspected malignant ventricular arrhythmias?
Absolute Event Rate: 21% vs 1.6%
The signal-averaged ECG accurately identifies patients at higher risk for malignant ventricular arrhythmias, regardless of unfiltered QRS duration.
Nalos et al. (1991) conducted a cohort in Suspicion for malignant ventricular arrhythmias (n=517). Presence of late potentials on signal-averaged ECG vs. Absence of late potentials was evaluated on Sudden death or recurrent sustained ventricular tachycardia. The presence of late potentials on signal-averaged ECG identified patients at a higher risk for sudden death or recurrent sustained ventricular tachycardia (overall 21% vs 1.6% without late potentials).
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