Key result
SAVR with concomitant aortic surgery in bicuspid aortic valve yields ~68% 20-year survival.
Why the study?
Clinical data on patient characteristics and long-term survival in the less common adult purely BAV population undergoing SAVR with concomitant aortic surgery were limited.
Does surgical aortic valve replacement with concomitant aortic surgery result in good long-term survival in adult patients with purely bicuspid aortic valve and aortopathy?
Cohort (n=48)
No
Does surgical aortic valve replacement with concomitant aortic surgery result in good long-term survival in adult patients with purely bicuspid aortic valve and aortopathy?
Surgical aortic valve replacement with concomitant aortic surgery in purely bicuspid aortic valve patients yields excellent long-term survival, approaching that of the general population.
Answers are grounded in this paper and cite their sources.
May inform decisions in pure BAV aortopathy; extends sparse Sievers 0 data but remains hypothesis-generating pending larger studies.
The bicuspid aortic valve (BAV) is the most common congenital cardiac malformation associated with aortopathy. The current study provides surgical clinical data on the patient characteristics and long-term survival of this less common adult purely BAV population undergoing surgical aortic valve replacement (SAVR) with concomitant aortic surgery. Adult patients with purely BAV who underwent SAVR and concomitant aortic surgery were included. Prevalence, predictors of survival, and outcomes for this patient population were analyzed. A total of 48 patients (mean age 58.7 ± 13.2 years, 33% female) with purely BAV underwent SAVR and concomitant aortic surgery between 1987 and 2016. The majority (62%) of the patients had pure aortic stenosis (AS). A total of 12 patients died. Survival was 92%, 73%, and 69% at 1, 5, and 20 years of follow-up. At 15 years of follow-up, the survival was close to that of the Dutch population, with a relative survival of 77%. Adult patients with a purely bicuspid aortic valve morphology undergoing SAVR and concomitant aortic root and/or ascending aorta present with excellent survival.
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Çelik et al. (2021) conducted a cohort in Purely bicuspid aortic valve (BAV) with associated aortopathy (n=48). Surgical aortic valve replacement with concomitant aortic surgery vs. Age-, sex-, and calendar year-matched Dutch general population was evaluated on Survival at 20 years. Surgical aortic valve replacement with concomitant aortic surgery in patients with purely bicuspid aortic valve resulted in 68% survival at 20 years, with a relative survival of 77% compared to matched controls at 15 years.
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