Key result
Bicuspid aortic valve was not associated with more pronounced ascending aorta dilatation, adverse aortic events, or death compared to tricuspid aortic valve after isolated aortic valve replacement.
Why the study?
Does isolated aortic valve replacement in patients with a bicuspid aortic valve lead to greater dilatation of the ascending aorta compared to those with a tricuspid aortic valve?
Cohort (n=613)
Does isolated aortic valve replacement in patients with a bicuspid aortic valve lead to greater dilatation of the ascending aorta compared to those with a tricuspid aortic valve?
Answers are grounded in this paper and cite their sources.
Dilatation of the ascending aorta occurs after isolated AVR regardless of whether the patient had a bicuspid or tricuspid aortic valve, with no significant difference in expansion rate or adverse events between the two groups.
Objective To compare the aortic diameter after isolated aortic valve replacement (AVR) in patients with a bicuspid (BAV) or tricuspid aortic valve (TAV) and an initially normal ascending aorta. Methods Patients with an ascending aortic diameter of < 45 mm who had undergone isolated AVR were studied. Ultrasonic cardiographic measurements of the ascending aortic diameter made pre- and postoperatively and follow-up data concerning adverse aortic events and death were analyzed. Results A total of 613 patients were included in this retrospective study; of these, 211 had a BAV and 402 had a TAV. In both groups, the ascending aorta significantly expanded but was non-aneurysmal during follow-up; however, the difference between the two groups was not significant. Cox regression analysis showed no significant effect associated with the presence of a BAV on adverse aortic events or death. Conclusion Dilatation of the ascending aorta was observed after AVR in both groups, but was not more pronounced in patients with a BAV. Long-term follow-up for ascending aortic aneurysm is necessary after AVR in both patients with a BAV and those with a TAV.
No takes yet. Share an insight, caveat, or question.
Zhang et al. (2016) conducted a cohort in Isolated aortic valve replacement with initially normal ascending aorta (n=613). Bicuspid aortic valve vs. Tricuspid aortic valve was evaluated on Ascending aortic diameter expansion, adverse aortic events, and death. Bicuspid aortic valve was not associated with more pronounced ascending aorta dilatation, adverse aortic events, or death compared to tricuspid aortic valve after isolated aortic valve replacement.
Synapse has enriched 10 related papers. Consider them for comparative context: